8th Asia Pacific Conference on Exercise and Sports Science 2017
Name: Wook Song, Ph.D.
Address: Department of Kinesiology, Institute of Sports Science / Institute on Aging
Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Korea
Prof. Dr. Wook SONG is a Professor of the Institute of Sports Science, Seoul National University. He received his Ph.D. in the Department of Health and Kinesiology at Texas A&M University in 2003 followed by a postdoctoral training in the Barshop Institute of Longevity and Aging Studies at the University of Texas Health Science Center at San Antonio from 2003 to 2006. His research interests include sarcopenia, sarcopenic obesity, myokine, and physical exercise intervention for the elderly and metabolic impairment. His research work has been published in influential journals including FASEB Journal, Antioxidant & Redox Signaling, Free Radical Biology & Medicine, Journal of Biological Chemistry, and Diabetes Care. Dr. Song has been the recipients of many research awards including the 2003 Recognition Award of the American Physiological Society, the 2003 Glenn/American Federation for Aging Research Scholarship for Research in the Biology of Aging, the 2004 Military Physiology Award of the American Physiological Society, the 2006 Caroline tum Suden/Frances A. Hellebrand Professional Opportunity Award of the American Physiological Society, the 2007 & 2008 Outstanding Research Award for Faculty of the Seoul National University, and the 2012 & 2014 Citation Award of the Korean Society for the Study of Obesity. Currently, Prof. Song is serving as a vice director of the Institute on Aging in Seoul National University, vice president of the Korean Academy of Sports Science and Exercise Medicine and the Korean Society for Exercise Nutrition, and executive board member of the Korean Society for Health Promotion and Disease Prevention and the Korean Society of Exercise Physiology.
Exercise-induced myokines in health and metabolic diseases
Skeletal muscle has been emerging as a research field since the past two decades. Contraction of a muscle, which acts as a secretory organ, stimulates production, secretion, and expression of cytokines or other muscle fiber-derived peptides, i.e., myokines. Exercise-induced myokines influence crosstalk between different organs in an autocrine, endocrine,or paracrine fashion. Myokines are recently recognized as potential candidates for treating metabolic diseases through their ability to stimulate AMP-activated protein kinase signaling, increase glucose uptake, and improve lipolysis. Myokines may have positive effects on metabolic disorders, type 2 diabetes, or obesity. Numerous studies on myokines suggested that myokines offer a potential treatment option for preventing metabolic diseases. This review summarizes the current understanding of the positive effects of exercise-induced myokines, such as interleukin-15, brain-derived neurotrophic factor, leukemia inhibitory factor, irisin, fibroblast growth factor 21, and secreted protein acidic and rich in cysteine, on metabolic diseases.